Dual regulation of Ca2* homeostasis by mechanical stress in bovine aortic endothelial cells
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چکیده
منابع مشابه
Mechanical stress-induced Ca2+ entry and Cl- current in cultured human aortic endothelial cells.
A fluid stream through a microtube was applied to cultured human aortic endothelial cells to investigate the endothelial responses of both the ionic currents and intracellular Ca2+concentration ([Ca2+]i) to mechanical stimulation. The fluid stream induced an increase in [Ca2+]ithat was dependent on both the flow rate and the extracellular Ca2+ concentration. Gd3+ and niflumic acid inhibited the...
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Diamide is a membrane-permeable, thiol-oxidizing agent that rapidly and reversibly oxidizes glutathione to GSSG and promotes formation of protein-glutathione mixed disulfides. In the present study, the acute effect of diamide on free cytosolic Ca2+ concentration ([Ca2+]i) was examined in fura-2-loaded bovine aortic endothelial cells. At low concentrations (50, 100 μM), diamide reversibly increa...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1997
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)44674-x